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Quicklook is the part of OS X, which takes care of thumbnails and the preview when you press the space bar.
Normally it only supports a few types of files, but programs like office and Photoshop install additional plugin's. Maybe one of those plugins is causing your problem.
You can drag the plugin to the desktop to disable it, then restart to see if it made a difference.
The folder is located in /Library/Quicklook and in your "home folder"/Library/Quicklook.
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