It boils down to how much of your work/life balance is compromised and whether the new positions will really get you somewhere internally or not.
If I were offered a "senior" job posting in my company for an extra $10,000 but expected to put in an extra 2 or 3 hours every day of my work week and/or weekends, with nowhere to go afterwards, then forget it. I'm better off where I am now.
Then again, some people love a fancy title. For me - FTS.
