These are the steps in building a $20,000-$30,000 MurderBox:
Case Mod Daniel’s murderbox – 008 / Final Abridged Version (page 1 loaded w/ images!) - bit-tech.net Forums
CPU's releasing soon are AMD Bulldozer > SandyBridge-E X79 Chipset and LGA 2011 socket > Ivy Bridge back to LGA1155. (Q2 2012)
I myself will wait for Ivy Bridge, even though SB-E X79 chipset looks very tempting...