Quote:
Originally Posted by Fcukedd
Anyone remember if Nabyl did any scaling for the CHEM281 final?
And do you remember if the exam was based off of new material of an equal blend of the older stuff?
Going in with ~ 70%, but absolutely clueless about Spectroscopy
Thanks
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my 281 final, there was a few minor points on the earlier stuff (i.e. naming, chirality, picking the most basic hydrogen/the most acidic, drawing different resonance structures, etc.) and a large proportion on the newer stuff synthesis reactions (282 final was all synthesis type questions) etc.
NMR / IR was on the final exam and it is not unlikely that he will give you the chemical equation, the IR, the NMR (and no IR/NMR tables so you must memorize) and he'll ask you to draw the structure. A large portion of my class screwed this up beautifully.
It's usually a fairly simple benzene-based structure, so just look for characteristic splitting patterns in the hydrogens which will tell you the symmetry, if there is any (there usually is since it is usually benzene based).
Oh, and keep your SN1/SN2/E1/E2 chemistry memorized inside and out, know the chirality/sterics/backside vs. front side attack for all of those, and know which conditions favor which.
There was also a question on my 281 final about thermodynamic vs. kinetic product, which conditions favor which, why, etc.
There's lots of good videos on youtube (especially by freelanceteach) that go thru ochem 1 and 2 step-by-step.
Good luck!
EDIT: Oh, also memorize any reactions he specifically mentioned in class as being the "only way to get XX product" -- The names/reactants are escaping me now, but there was only one reactions used only to get a C-terminal alcohol, another reaction on my 281 final required the use of an epoxide as a reagent, which screwed up a lot of people