I love my wheel guns - I picked up another Dan Wesson 15-2 with supposedly less than 50 rounds and I'd believe it because when I took it apart there was no wear, no dirt, and the 8" and 6" barrel have never been fired.
I don't know if you ever plan on competing - even just Club shoots, often only allow 6 shots. The 7 shot S&W needs specific speed loaders etc. I never read a lot about their backstrap strengths, as that was a concern on some of the S&W models for years.
The twins:
Not even dirty inside: