I only use Airbnb for multi-generation or multi-family trips where you want to share a space together. Kids love it cause they can run around and discover the space with their peers. And little things like enjoying home cooking, and saving on stupid things like breakfast starts to add up. Seriously, it's criminal to pay $10+/person for ham and eggs when you can make it for a dollar as long as you have a kitchen.
In the end, it's all about the company. If there's people present that I don't want to share the space with (ie. whiny kids), I'd opt for a hotel any day.