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With Down syndrome, I thought it can be detected during pregnancy. So it wasn't very much of a concern to me. But I was concerned about the risk of the baby having other developmental issues, and AFAIK, that risk level goes up with age, and really starts shooting up after 35.
Prior to having our child, my wife and I also had a mutual understanding/agreement that if there were any serious issues being detected in the fetus, we would abort and terminate the pregnancy, and Down syndrome was precisely the example we used in our discussion. Fortunately, we never had to really make that decision.
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